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  • Produktbild: Side Reactions in Peptide Synthesis
  • Produktbild: Side Reactions in Peptide Synthesis

Side Reactions in Peptide Synthesis

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Beschreibung

Side Reactions in Peptide Synthesis, based on the author's academic and industrial experience, and backed by a thorough review of the current literature, provides analysis of, and proposes solutions to, the most frequently encountered side reactions during peptide and peptidomimetic synthesis.

This...

Beschreibung

Side Reactions in Peptide Synthesis, based on the author's academic and industrial experience, and backed by a thorough review of the current literature, provides analysis of, and proposes solutions to, the most frequently encountered side reactions during peptide and peptidomimetic synthesis.

This valuable handbook is ideal for research and process chemists working with peptide synthesis in diverse settings across academic, biotech, and pharmaceutical research and development.

While peptide chemistry is increasingly prevalent, common side reactions and their causes are often poorly understood or anticipated, causing unnecessary waste of materials and delay.

Each chapter discusses common side reactions through detailed chemical equations, proposed mechanisms (if any), theoretical background, and finally, a variety of possible solutions to avoid or alleviate the specified side reaction.

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

08.09.2015

Verlag Elsevier Science & Technology
Seitenzahl

376

Produktdetails

Einband

Gebundene Ausgabe

Erscheinungsdatum

08.09.2015

Verlag Elsevier Science & Technology
Seitenzahl

376

Maße (L/B/H)

23,6/15,6/3 cm

Gewicht

682 g

Sprache

Englisch

ISBN

978-0-12-801009-9

EU-Ansprechpartner

Elsevier B.V.
Radarweg 29
1043 NX Amsterdam
NL
productsafety@elsevier.com

Herstelleradresse

Elsevier Science & Technology
London Wall 125
EC2Y 5AS London
GB
tradeorders@elsevier.com

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  • Produktbild: Side Reactions in Peptide Synthesis
  • Produktbild: Side Reactions in Peptide Synthesis
    1. Peptide Fragmentation/Deletion
    2. Premature FMOC Deprotection
    3. Elimination Side Reactions
    4. Peptide Global Deprotection/Scavenger-Induced Side Reactions
    5. Peptide Rearrangement Side Reactions
    6. Side Reactions Occurring at Amino Acid/Peptide Activation Step
    7. Intramolecular Cyclization Side Reactions
    8. Side Reactions in Amino Groups in Peptide Synthesis
    9. Side Reactions in Hydroxyl, Carboxyl, Ester Groups in Peptide Synthesis
    10. Oxidation and Reduction Side Reactions in Peptide Synthesis
    11. Racemization in Peptide Synthesis
    12. Solvent and Residual Impurities in the Reagents Induced Side Reactions
    13. Dipeptide Formation Side Reactions (Redundant Amino Acid Incorporation)
    14. Reattachment of Peptides to the Solid Supports
    15. Addition Side Reactions in Peptide Synthesis
    16. Side Reactions in Phosphor Peptides
    17. Side Reactions in CYS
    18. Protein Fragmentations